II. Indication
- Refractory Rheumatoid Arthritis
- Combined with Methotrexate and other DMARDs
- Corticosteroid sparing in agents
- Juvenile Rheumatoid Arthritis
- Psoriatic Arthritis
III. Mechanism
- Soluble TNF receptor blocker
IV. Efficacy
- Rapid onset and very effective
- Arrests XRay progression
- Good synergistic effect with Methotrexate
V. Adverse Effects
- Potential risk of infection
- No significant adverse effects
VI. Dosing
- Preloaded vial or syringe: 25 mg SQ twice weekly or 50 mg SC weekly
VII. Cost
- Per vial: $150
- Per month: $1200
- Per year: $14,000
VIII. Monitoring
- Consider following Complete Blood Count
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