II. Indication
- Second line Tuberculosis management agent
- Second line agent in Pneumocystis carinii Pneumonia
- First line in certain autoimmune Bullous Conditions
III. Dose
- Dapsone 100 mg per day
IV. Adverse Effects
- Hemoglobin decreased (1-2 grams)
- Reticulocytes increased (2-12%)
- Hemolysis in G6PD Deficiency
- Methemoglobinemia
- Peripheral Neuropathy (rare)
- Nausea or Vomiting
- Proteinuria or Albuminuria
- Nephrotic Syndrome
- Erythema Nodosum leprosum in Leprosy treatment (50%)
V. Contraindications
VI. Monitoring
-
Glucose-6-Phosphate Dehydrogenase Deficiency (G6PD)
- Screen for before starting Dapsone
-
Complete Blood Count
- Obtain baseline and monthly while on Dapsone
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Related Studies
| dapsone (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| DAPSONE 100 MG TABLET | Generic | $1.02 each |
| DAPSONE 25 MG TABLET | Generic | $0.57 each |
| DAPSONE 5% GEL | Generic | $2.39 per gram |
| DAPSONE 7.5% GEL PUMP | Generic | $2.28 per gram |