II. Indications

  1. Herpes Zoster (Shingles)
  2. Genital Herpes (initial, recurrent or prophylaxis)
  3. Herpes Labialis (Oral Herpes)

III. Dosing

  1. Herpes Labialis (Cold Sores)
    1. Adult: 2 grams PO q12 hours for 1 day
  2. Herpes Zoster (Shingles)
    1. Adult: 1 gram tid for 7 days
  3. Genital Herpes
    1. Initial: 1 gram PO bid for 10 days
    2. Recurrent: 500 mg PO bid for 3 days
    3. Prophylaxis (for up to 1 year)
      1. Immunocompetent (<9 episodes/year): 500 mg PO qd
      2. Immunocompetent (9 or more per year): 1000 mg PO qd
      3. HIV with CD4>100: 500 mg PO bid

IV. Adverse Effects

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Cost: Medications

valacyclovir (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
VALACYCLOVIR HCL 1 GRAM TABLET Generic $0.51 each
VALACYCLOVIR HCL 500 MG TABLET Generic $0.28 each
valtrex (on 9/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
VALTREX 1 GM CAPLET Generic $0.51 each
VALTREX 500 MG CAPLET Generic $0.28 each