III. Efficacy

  1. Very effective in combination with Zidovudine (AZT)

IV. Adverse Effects

  1. See nRTI for adverse effects attributed to the class
  2. Generally Well tolerated
  3. Similar adverse effects to Zidovudine (AZT) but much less severe
    1. Gastrointestinal upset
    2. Neutropenia
  4. Hepatitis B infection flares on Medication Withdrawal

V. Dosing

  1. Adults: 150 mg twice daily or 300 mg orally daily

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Cost: Medications

lamivudine (on 11/23/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
LAMIVUDINE 150 MG TABLET Generic $0.85 each
LAMIVUDINE 300 MG TABLET Generic $1.29 each
LAMIVUDINE HBV 100 MG TABLET Generic $1.64 each