II. General
- Evaluate and treat specific Vertigo Causes
- Medications are indicated for symptomatic acute Vertigo
- Medications decrease symptoms, but do NOT treat the underlying pathology
- Avoid use of symptom control medications >3 days
- Early ambulation improves rate of recovery
- Rehabilitation Exercises
- Epley Maneuver
- Indicated for Benign Paroxysmal Positional Vertigo (BPPV)
- Prescribed program of head movements and activity
- Improves symptom adaptation and balance
- Yardley (2004) Ann Intern Med 141:598-605 [PubMed]
- Epley Maneuver
III. Management: Symptomatic Therapy - Outpatient
- Precautions
- Limit to 3 days only (to allow central compensation to proceed)
- Over the counter medications (Category B in pregnancy)
- Antihistamines risk Anticholinergic side effects (sedation, Urinary Retention, Altered Mental Status, Blurred Vision, falls in elderly)
- Meclizine (Antivert)
- Age >12 years: 25 mg orally every 6 hours as needed
- Precaution: Sedating
- Dimenhydrinate (Dramamine)
- Preferred as better Anti-emetic effect and less sedation than Meclizine
- Adults: 50-100 mg orally every 4-6 hours (max: 400 mg/day)
- Age 2-5: 12.5-25 mg orally every 6-8 hours (max: 75 mg/day)
- Age 6-12: 25-50 mg orally every 6-8 hours (max: 150 mg/day)
-
Antiemetics
- Ondansetron ODT (Zofran ODT) 4 mg IV/IM/PO every 6 hours as needed
- Metoclopramide (Reglan) 10 mg orally every 6 hours as needed
-
Benzodiazepines for severe symptoms (adult dosing)
- Avoid Benzodiazepines in most cases of outpatient Vertigo Management
- Lower efficacy when compared with Antihistamines
- Higher risk of respiratory depression, falls in elderly and dependency/misuse
- Diazepam (Valium) 5-10 mg orally every 6 hours
- Lorazepam (Ativan) 0.5-2 mg orally every 6 hours
- Avoid Benzodiazepines in most cases of outpatient Vertigo Management
IV. Management: Symptomatic Therapy - Emergency Department
- First Line agents with dual Anti-emetic and anti-Vertigo activity
- Promethazine (Phenergan)
- Dose: 6.25 to 12.5 mg slow IV push (or 12.25 to 25 mg IM/PO/PR) as needed every 6 hours
- Consider Ondansetron instead in the elderly due to Anticholinergic effects
- Dimenhydrinate (Dramamine)
- Dose: 50 mg IV every 4 to 6 hours prn
- IV preparation has limited availability (oral tablets may be used if Vomiting is controlled)
- Promethazine (Phenergan)
- Bicarbonate and Diphenhydramine protocol (dosing based on Taiwan protocol, needs modification for use in U.S.)
- Diphenhydramine 30 mg in 100 ml Normal Saline IV
- Sodium Bicarbonate 66.4 mEq (1.5 ampules bicarbonate) slowly pushed for 2 minutes
- Chi (2025) JAMA Netw Open 8(11):e2541472 +PMID: 41196596 [PubMed]
- Other Anti-emetics
- Prochlorperazine (Compazine) 5-10 mg IV/IM every 3-4 hours as needed
- Ondansetron (Zofran) 4 mg IV/IM/PO every 6 hours as needed
- Severe Vertigo symptoms (esp. if preparing for MRI tolerance)
V. References
- Ondrejka (2014) Crit Dec Emerg Med 28(10): 11-7
- Marill (2000) Ann Emerg Med 36:310-9 [PubMed]
- Swartz (2005) Am Fam Physician 71:1115-30 [PubMed]