II. Indications: Paradise Criteria for Tonsillectomy in Children
- Frequency Criteria: Minimum number of Pharyngitis episodes
- Past 1 year: 7 episodes
 - Past 2 years: 5 episodes per year for both years
 - Past 3 years: 3 episodes per year for all three years
 
 - Episode Criteria: Each Pharyngitis episode must include at least ONE of the following criteria in addition to Sore Throat
- Temperature >100.9 F (38.3 C)
 - Tender cervical adenopathy or cervical Lymph Nodes >2 cm in size
 - Tonsillar exudate
 - Group A Beta Hemolytic Streptococcus Culture positive
 
 - Treatment Criteria: Each Pharyngitis episode must have been treated with standard protocol
- Antibiotics at conventional dosing for suspected or proven Streptococcal Pharyngitis
 
 - Documentation Criteria
- Medical record documents each Pharyngitis episode including above criteria or
 - Observation by clinician for at least 2 subsequent episodes that meet above criteria, typically over a 12 month period
 
 
III. Indications: Modifying Factors which may indicate Tonsillectomy (if Paradise criteria not met)
- 
                          Sleep disordered breathing (e.g. pediatric Sleep Apnea)
- Witnessed snoring, apneas or gasping for air
 - Obstructive Sleep Apnea by Polysomnogram
 
 - Difficult management of frequent Pharyngitis
- Multiple drug allergies
 - Intolerance to medications
 
 - Complicated Pharyngitis cases
 - Miscellaneous unproven indications
- Based on clinical judgement and Informed Consent regarding risks versus benefits
 - Halitosis
 - Febrile Seizures
 - Malocclusion
 
 - 
                          Tonsillar size is not an indication for surgery
- Exception: Related complication such as sleep disordered breathing
 - Size diminishes naturally in early adolescence
 
 
IV. Management: Postoperative bleeding from Tonsillectomy
- Typically occurs at day 5-7 (up to day 10) after Tonsillectomy
- Related to sloughing of eschar (Fibrin clot)
 - Occurs in 2-7% of post-Tonsillectomy cases
- Newer intracapsular techniques have bleeding rates <1%
 
 - Of those with mild Tonsillar bleeding, 40% may go on to have major bleeding in next 24 hours
- Teenagers and adults are more likely than younger children to require surgical intervention
 
 
 - Secure airway if needed
- See Advanced Airway
 
 - Consider gargled Tranexamic Acid (TXA) 5% Mouthwash
- https://rebelem.com/topical-tranexamic-acid-epistaxis-oral-bleeds/
 - Prepare Tranexamic Acid (TXA) 5% Mouthwash
- Tranexamic Acid (TXA) is available in 1000 mg/10 ml vials that contain 10 ml
 - Prepare 2 small cups each of 5 ml TXA (500 mg) and 5 ml cold water (10 ml of diluted TXA per cup)
 - Alternatively a 500 mg TXA tablet may be dissolved in 10-15 ml water
 
 - Have patient gargle 10 ml for 1-2 minutes and then gently spit out solution
 - May repeat again in 10-15 minutes
 
 - Consider nebulized Tranexamic Acid (TXA)
- Nebulize 500 mg (children) or 1000 mg adults (case reports)
 - Hankerson (2015) J Palliat Med 18(12): 1060-2 [PubMed]
 
 - Consider Nebulized racemic epinephrine
- May Vasoconstrict Tonsillar region vessels
 - Anecdotally, Tranexamic Acid may be more effective
 
 - Local Bleeding Control
- Insert bite block
 - Anesthetize area (cetacaine or atomized Lidocaine via MADD)
 - Apply pressure with finger to bleeding site
 - Apply Tranexamic Acid or Epinephrine soaked gauze directly against bleeding site with McGill forceps
 - Inject Epinephrine into bleeding site
 
 - Disposition
- Bleeding continues
- Transfer emergently to otolaryngology
 - Secure airway as needed
 - Replace Blood Products as needed
 
 - Bleeding stops
- Consult otolaryngology
 - Typically transfer to otolaryngology for evaluation, management and observation
 
 
 - Bleeding continues
 
V. Management: Postoperative Pain
- Liquid Analgesics
- Ibuprofen 10 mg/kg up to 600 mg orally every 6 hours
- Does NOT appear to increase Hemorrhage risk and very effective for postoperative pain
 - However, unlike Ibuprofen, Toradol does increase Hemorrhage risk (esp. in age >18 years old, see below)
 
 - Acetaminophen 15 mg/kg up to 650 mg orally every 6 hours
 - Oxycodone or Morphine for breakthrough pain
- Risk of apnea in patients with history of Obstructive Sleep Apnea (Brainstem tolerance for CO2 retention)
 
 
 - Ibuprofen 10 mg/kg up to 600 mg orally every 6 hours
 - Other measures
- Maluka honey lozenges or popsicles (OTC)
 - Dexamethasone
- Dexamethasone 0.5 mg/kg (up to 10 mg) scheduled on day 3 post-operatively (consider repeat dose on day 5)
 - Greenwell (2021) Otolaryngol Head Neck Surg 165(1):83-8 +PMID: 33228459 [PubMed]
 
 
 - Emergency department
- Consider Dexamethasone if not already dosed (see above)
 - Intravenous Fluids
 - Avoid Toradol
- Unlike Ibuprofen, Toradol increases the risk of Hemorrhage up to 5-fold (esp. in age >18 years old)
 - Mixed results in study
 
 
 
VI. Resources
- Clinical Practice Guideline for Tonsillectomy in Children
 
VII. References
- Claudius, Behar and Hofmann, Santillanes, Bowman in Herbert (1018) EM:Rap 18(6):13-4
 - Claudius, Behar and Stoner in Herbert (2015) EM:Rap 15(11):2-3
 - Wiedermann (2024) Mayo Clinic Pediatric Days, attended lecture 1/18/2024
 - Baugh (2011) Otolaryngol Head Neck Surg 144(1): S1-S30 [PubMed]
 - Randel (2011) Am Fam Physician 84(5): 566-73 [PubMed]