III. Pathophysiology

  1. Decreased vascular supply to nail bed

IV. Associated Conditions

  1. Liver disease (hepatic Cirrhosis)
    1. Most common cause (occurs in 80% of Cirrhosis)
  2. Diabetes Mellitus
  3. Congestive Heart Failure
  4. Hyperthyroidism
  5. Aging

V. Signs

  1. Proximal 80% of nail is white
  2. Distal band (1-2 mm wide) of nail is normal pink color
  3. Lunula destroyed

VI. Differential Diagnosis

VII. Reference

  1. Habif (2004) Clinical Dermatology p. 885
  2. Terry (1954) Lancet, 1:757 [PubMed]

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