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GlucosamineAka: Glucosamine Sulfate
- See Also
- Pathophysiology
- Glucosamine is endogenous amino sugar, a precursor of glycosaminoglycans
- Glycosaminoglycans are present in joint structures such as Synovial Fluid
- Effects
- Stimulates chondrocyte metabolism
- May have anti-inflammatory effects at higher dose
- Source
- Marine exoskeleton or
- Synthetically derived
- Efficacy
- Dosing
- Glucosamine 1500 mg orally once daily or 500 mg orally three times daily
- Adverse Effects
- Gastrointestinal upset
- Hemoglobin A1C and Serum Glucose are NOT impacted (contrary to initial reports)
- Scroggie (2003) Arch Intern Med 163:1587-90
- Glucosamine is safe in shellfish allergy (despite marine exoskeleton source)
- References
Glucosamine (C0017718) | |
|---|---|
| Definition (CSP) | amino sugar derivative of glucose, substituted at the 2 position, occurring in glycosaminoglycans and a variety of complex polysaccharides such as blood group substances. |
| Concepts | Carbohydrate (T118) , Pharmacologic Substance (T121) |
| MSH | D005944 |
| English | 2 Amino 2 Deoxyglucose, 2-Amino-2-Deoxyglucose, Glucosamine, GLUCOSAMINE PREPARATION, Glucosamine product, Glycosamine |
| Spanish | glicosamina, glucosamina |
| Parent Concepts | Hexosamines (C0019478), Unclassified Ingredients (C1372954), Unclassified Ingredient Preparations (C1377282), Amino Sugars (C0002531), Over the counter healthfood/herbal products (C0361218), Drug allergen (C1320237), Alternative medicine preparation (C1527378), Alternative medicine agent (C1626216) |
| Sources | CSP, MSH, MTH, NDFRT, RXNORM, SCTSPA, SNOMEDCT, VANDF Derived from the NIH UMLS (Unified Medical Language System) |