Pharmacology Book

Miscellaneous

  • Placebo Effect

http://www.fpnotebook.com/

Placebo EffectAka: Placebo

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  1. Definition
    1. Therapy not relevant to condition being treated
    2. Dummy medication used for control group
    3. Latin derivation: I will please
  2. General
    1. Response to placebo: 20-30% of study participants
  3. Efficacy
    1. Meta-analysis shows no therapeutic benefit
    2. Avoid in clinical practice (aside from studies)
    3. References
      1. Hrobjartsson (2001) N Engl J Med 344:1594

Placebos (C0032042)

Definition (MSH)Any dummy medication or treatment. Although placebos originally were medicinal preparations having no specific pharmacological activity against a targeted condition, the concept has been extended to include treatments or procedures, especially those administered to control groups in clinical trials in order to provide baseline measurements for the experimental protocol.
Definition (CSP)pills, injections, or treatments missing the active component of interest, administered to experimental control groups to correct for nonspecific effects.
Definition (NCI)An inactive substance, treatment, or procedure that is intended to mimic as closely as possible a therapy in a clinical trial.
Definition (PDQ)An inactive substance, treatment or procedure that is intended to provide baseline measurements for the experimental protocol of a clinical trial. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43469&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43469&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C753" NCI Thesaurus)
Definition (NCI)An inactive substance, treatment or procedure that is intended to provide baseline measurements for the experimental protocol of a clinical trial.
ConceptsTherapeutic or Preventive Procedure (T061)
Englishplacebo, Placebos, PLCB, sham therapy, Sham Treatment
CreditsDerived from the NIH UMLS (Unified Medical Language System)



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