Obstetrics Book

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Chorionic Villus Sampling

Aka: Chorionic Villus Sampling
  1. See Also
    1. Antenatal Screening
  2. Definition
    1. Definitive, first trimester Antenatal Screening for fetal chromosomal abnormalities
  3. Indications
    1. Antenatal Screening for fetal chromosomal abnormalities for high risk pregnancies
  4. Protocol
    1. Performed between 10-13 weeks gestation
    2. Placental tissue sampling techniques
      1. Transabdominal sampling
      2. Transcervical sampling
        1. Higher Incidence of pregnancy loss than with abdominal sampling
        2. Indicated if placenta posterior or bowel blocks abdominal sampling
  5. Adverse Effects
    1. Pregnancy loss
      1. Risk: 0.6 to 4.6% (higher rate than with Amniocentesis)
    2. Limb reduction defects
      1. Gestational age 10-13 weeks: Risk does not exceed general population risk (6 per 10,000)
      2. Gestational age <10 weeks: 1-2% risk of limb reduction defect
  6. Efficacy: Down Syndrome detection
    1. Test Sensitivity: 97.8%
    2. Test Specificity: 98-99%
  7. References
    1. Anderson (2009) Am Fam Physician 79(2): 117-24
    2. Caughey (2006) Obstet Gynecol 108: 612-6

Chorionic Villi Sampling (C0008509)

Definition (NCI) The extraction of placenta tissue containing the chorionic villi from the maternal uterus in early pregnancy to screen for fetal genetic defects.
Definition (MSH) A method for diagnosis of fetal diseases by sampling the cells of the placental chorionic villi for DNA analysis, presence of bacteria, concentration of metabolites, etc. The advantage over amniocentesis is that the procedure can be carried out in the first trimester.
Definition (CSP) technique to sample fetal tissue for genetic analysis; may be performed after 6 weeks gestation, which is earlier than amniocentesis, facilitating elective abortion.
Concepts Diagnostic Procedure (T060)
MSH D015193
ICD10 16603-00
SnomedCT 150020005, 303720006
CPT 59015
English Biopsies, Chorionic Villi, Biopsy, Chorionic Villi, Chorionic Villi Biopsies, Chorionic Villi Biopsy, Chorionic Villi Sampling, Chorionic Villi Samplings, Chorionic Villus Sampling, Chorionic Villus Samplings, Sampling, Chorionic Villi, Sampling, Chorionic Villus, Samplings, Chorionic Villi, Samplings, Chorionic Villus, Chorionic villus sampling, CVS - Chorionic villus samp, Chorionic villus sampling, any method, CHORIONIC VILLUS SAMPLING, ANY METHOD, chorionic villus sampling (procedure), chorionic villi sampling, chorionic villus sampling, Biopsy chorionic villous, Biopsy chronic villous, CVS, chorionic villus sampling (CVS), chorionic villi biopsy, CVB - Chorionic villus biopsy, CVS - Chorionic villus sampling, Sampling of chorionic villus, Sampling of chorionic villus (procedure), CHORION BIOPSY, Chorion biopsy, CHORNC VILLUS SAMPLING
French Biopsie des villosités chorioniques, Prélèvement de villosités choriales, Biopsie des villosités choriales, Biopsie du trophoblaste, Placentocentèse, PVC (Prélèvement de Villosités Choriales), Choriocentèse, Biopsie de trophoblaste
German Biopsie Chorionzotten, Biopsie, Chorionzotten-, Chorionbiopsie, Chorionzottenbiopsie, Chorionzottenuntersuchung
Portuguese Biopsia de vilosidades coriónicas, Biopsia de vilosidades coriais, Amostra da Vilosidade Coriônica, Biópsia da Vilosidade Coriônica
Spanish Biopsia vellosa crónica, Sampling of chorionic villus, Toma de muestra de vellosidad corionica, cualquier metodo, obtención de muestra de vellosidades coriónicas (procedimiento), obtención de muestra de vellosidades coriónicas, Biopsia de vellosidades coriónicas, Biopsia de la Vellosidad Corionica, Muestra de la Vellosidad Corionica, Biopsia de la Vellosidad Coriónica, Muestra de la Vellosidad Coriónica
Japanese 絨毛生検, ｼﾞｭｳﾓｳｾｲｹﾝ, 絨毛診断, 絨毛穿刺, 絨毛膜絨毛生検, 絨毛膜絨毛試料採取, 生検-絨毛膜絨毛
Swedish Korionbiopsi
Czech choriové klky - odběr, Biopsie choriových klků
Finnish Korionvillusbiopsia
Russian VORSINKI KHORIONA, VZIATIE PROB, KHORIONA VORSINOK BIOPSIIA, ВОРСИНКИ ХОРИОНА, ВЗЯТИЕ ПРОБ, ХОРИОНА ВОРСИНОК БИОПСИЯ
Italian Biopsia dei villi coriali, Prelievo dei villi coriali
Croatian KORIONSKI FRONDOZUM, BIOPSIJA
Polish Pobieranie próbek kosmków kosmówki, Biopsja kosmków kosmówki
Hungarian Chronic villus biopszia, Chorion villus biopszia
Dutch chorionvillusbiopsie, Biopsie, chorionvillus-, Chorionvillusbiopsie
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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