Infectious Disease Book

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Penciclovir CreamAka: Penciclovir, Denavir

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  1. Indications
    1. Herpes Labialis (Cold Sores)
  2. Dosing
    1. Penciclovir 1% Cream
    2. Start topical application at first symptoms
    3. Apply every 2 hours while awake for 4 days
  3. Efficacy
    1. Study n=1573, PCT showed significant improvement
      1. More than 0.5 days faster resolution, decreased pain
    2. Reference
      1. Spruance (1997) JAMA 277:1374

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