Infectious Disease Book

http://www.fpnotebook.com/

Famciclovir

Aka: Famciclovir, Famvir
  1. Indications
    1. Herpes Zoster (Shingles)
    2. Recurrent Genital Herpes
    3. Recurrent HSV in immunocompromised patients
  2. Dosing
    1. Herpes Zoster (Shingles)
      1. Adult: 500 mg PO q8 hours for 7 days
    2. Genital Herpes
      1. Initial: 250 mg PO tid for 7-10 days
      2. Recurrent immunocompetent: 125 mg PO bid for 5 days
      3. Recurrent in HIV: 500 mg PO bid for 7 days
      4. Prophylaxis: 250 mg PO bid for up to 12 months
  3. Pharmacokinetics
    1. Adjust dose for Creatinine Clearance <60 ml/min
  4. Adverse Effects
    1. Headache
    2. Nausea or Vomiting
    3. Fatigue
    4. Paresthesias
    5. Pruritus

famciclovir (C0209227)

Definition (NCI) A diacetyl 6-deoxy prodrug analog of the antiviral agent penciclovir. Orally administered, famciclovir in vivo is converted to penciclovir triphosphate, which is active against the Herpes viruses, including herpes simplex 1 and 2 and varicella-zoster. This agent inhibits the replication of viral DNA by interfering competitively with DNA polymerase. (NCI04)
Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH C060590
SnomedCT 387557001, 96097002
English 9-(4-acetoxy-3-(acetoxymethyl)but-1-yl)-2-aminopurine, famciclovir, famciclovir (medication), FAMCICLOVIR, famciclovir [Chemical/Ingredient], Famciclovir, Famciclovir product, Famciclovir (substance), Famciclovir (product)
Spanish famciclovir (producto), famciclovir (sustancia), famciclovir
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Famvir (C0591478)

Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH C060590
English Famvir, famvir
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Navigation Tree