II. Indications

  1. No definite indications
  2. Used with Activated Charcoal only for Gastrointestinal Decontamination
  3. Consider for potentially toxic amounts of sustained-release, enteric-coated, or poorly-bound drugs to actovated charcoal

III. Contraindications

  1. Examination findings
    1. Absent bowel sounds
    2. Recent abdominal surgery or Trauma
    3. Bowel perforation
    4. Intestinal Obstruction
    5. Dehydration
    6. Hypotension
  2. Poison ingestion of corrosive substance
  3. Poison ingestion with Diarrheal adverse effects
    1. Organophosphate Poisoning
    2. Carbamate Poisoning
    3. Heavy metal Poisoning
  4. Poison ingestion with ileus as adverse effect
    1. Paraquat
    2. Diquat

IV. Precautions

  1. Use only in combination with Activated Charcoal
  2. Avoid Oil Cathartics
    1. Risk of Lipoid Aspiration Pneumonia
    2. Risk outweighs any potential benefit

V. Protocol: Single dose only

  1. Sorbitol
    1. Adult: 1 to 2 ml/kg of 70% Sorbitol solution
    2. Child: 4.3 ml/kg of 35% Sorbitol solution
  2. Magnesium Citrate
    1. Adult: 250 ml Magnesium Citrate 10% solution
    2. Child: 4 ml/kg Magnesium Citrate 10% solution (up to 250 ml)

VI. Complications

  1. Electrolyte imbalance
  2. Dehydration
  3. Hypermagnesemia

VII. Contraindications

  1. Renal Failure
  2. Congestive Heart Failure
  3. Diarrhea
  4. Ileus
  5. Recent bowel surgery
  6. Electrolyte imbalance
  7. Extremes of age (under age 1 or over age 65 years)

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Ontology: Cathartics (C0007422)

Definition (MSH) Agents that are used to stimulate evacuation of the bowels.
Concepts Pharmacologic Substance (T121)
MSH D002400
SnomedCT 264319004, 64407005, 24570008
English Cathartics, Purgatives, Evacuants, Bowel, Bowel Evacuants, bowel evacuants, bowel evacuants (medication), GI preparations bowel evacuants, purgative, cathartic, cathartics, purgatives, Purgative (substance), Cathartic, Cathartic (substance), Cathartic, NOS, Purgative, NOS, Purgative
Spanish purgante, purgante (sustancia), catártico (sustancia), catártico, Purgantes, Catárticos
French Cathartiques, Agents cathartiques, Médicaments cathartiques, Purgatifs, Lavements évacuateurs
Swedish Laxermedel
Czech katartika, purgativa, purgancia
Finnish Ulostuslääkkeet (cathartics)
Italian Purgativi, Catartici
Russian SREDSTVA, USILIVAIUSHCHIE PERISTAL'TIKU KISHECHNIKA, POSLABLIAIUSHCHIE SREDSTVA, SREDSTVA, VYZYVAIUSHCHIE OPOROZHNENIE KISHECHNIKA, SLABITEL'NYE SREDSTVA, ПОСЛАБЛЯЮЩИЕ СРЕДСТВА, СЛАБИТЕЛЬНЫЕ СРЕДСТВА, СРЕДСТВА, ВЫЗЫВАЮЩИЕ ОПОРОЖНЕНИЕ КИШЕЧНИКА, СРЕДСТВА, УСИЛИВАЮЩИЕ ПЕРИСТАЛЬТИКУ КИШЕЧНИКА
Japanese 下剤, 瀉下剤, 軟下剤, 下薬, 便通薬
Polish Leki oczyszczające jelita
German Purgative, Abführmittel
Portuguese Catárticos, Purgantes