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RASTAka: RadioAllergoSorbent Test

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  1. Efficacy
    1. Highly specific for allergans
    2. Lower Test Sensitivity than allergy Skin Testing
  2. Indications
    1. Not recommended for food, venom, or drug allergies
    2. Alternative to Skin Testing in certain cases
      1. Skin Testing contraindicated
      2. Interfering medications (e.g. Antihistamines)
      3. Age <3 years
    3. Allergy Testing for common allergans
      1. Pet dander
      2. Dust mites
      3. Pollen
      4. Mold spores
  3. Screen Contents
    1. June Grass and cross reacting grasses
      1. Rye
      2. Sweet Vernal
      3. Timothy
      4. Brome
    2. Oak Tree
    3. Short ragweed
    4. Alternaria mold
    5. Dust mite
    6. Cat
  4. Technique
    1. Allergen coupled to a paper disc
    2. Patient's serum is added to paper disc
    3. Antigen-Antibody forms in the case of allergy
    4. Radioactive anti-IgE added and complexes with above
    5. Gamma counter scores binding
  5. RAST Scoring
    1. Class 0: 200-750 (No significant allergy)
    2. Class 1: 750-1600 (Mild allergy)
    3. Class 2: 1600-3600 (Moderate allergy)
    4. Class 3: 3601-8000
    5. Class 4: 8001-18000
    6. Class 5: 18001-40000 (Most allergic)

Radioallergosorbent Test (C0034554)

Definition (MSH)An in vitro allergen radioimmunoassay in which allergens are coupled to an immunosorbent. The coupled allergens bind the IgE in the sera of patients which in turn binds radioisotope-labeled anti-IMMUNOGLOBULIN E antibodies.
ConceptsLaboratory Procedure (T059)
MSHD011852
EnglishAllergens Radioimmunosorbent Assay, Allergens Radioimmunosorbent Assays, EAST test, Radio-allergosorbent test, Radioallergosorbent Test, Radioallergosorbent Tests, Radioimmunosorbent Assay of Allergens, RAST, RAST - Radio-allergosorbent test, RAST test
Spanishprueba radioalergosorbente, prueba RAST, RAST
Parent ConceptsImmunosorbent Techniques (C0021074), Radioimmunoassay (C0034580), Serologic tests (C0036743), Duplicate concept (C1274013), Allergen specific IgE antibody measurement by method (C1313955)
SourcesAOD, LCH, LNC, MSH, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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