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RAST
Aka: RAST, RadioAllergoSorbent Test
- Efficacy
- Highly specific for allergans
- Lower Test Sensitivity than allergy Skin Testing
- Indications
- Not recommended for food, venom, or drug allergies
- Alternative to Skin Testing in certain cases
- Skin Testing contraindicated
- Interfering medications (e.g. Antihistamines)
- Age <3 years
- Allergy Testing for common allergans
- Pet dander
- Dust mites
- Pollen
- Mold spores
- Screen Contents
- June Grass and cross reacting grasses
- Rye
- Sweet Vernal
- Timothy
- Brome
- Oak Tree
- Short ragweed
- Alternaria mold
- Dust mite
- Cat
- Technique
- Allergen coupled to a paper disc
- Patient's serum is added to paper disc
- Antigen-Antibody forms in the case of allergy
- Radioactive anti-IgE added and complexes with above
- Gamma counter scores binding
- RAST Scoring
- Class 0: 200-750 (No significant allergy)
- Class 1: 750-1600 (Mild allergy)
- Class 2: 1600-3600 (Moderate allergy)
- Class 3: 3601-8000
- Class 4: 8001-18000
- Class 5: 18001-40000 (Most allergic)