Otolaryngology Book

http://www.fpnotebook.com/

Atopic PatientAka: Atopic Triad, Atope, Atopy

Advertisement

  1. Associated Conditions
    1. Allergic Rhinitis
    2. Eczematous Dermatitis (Atopic Dermatitis)
    3. Asthma
  2. Allergic History
    1. Early Onset of Allergic Rhinitis
    2. Positive Family History of Atopy
    3. Seasonal Allergic Rhinitis symptoms
    4. Provocative Symptoms
      1. Worse with animal exposure
      2. Worse outdoors
      3. Worse near cut grass
      4. Better in air conditioning
    5. Tobacco and chemicals are not the primary cause
    6. History of prior relief with Immunotherapy
  3. Prevention
    1. See Allergan Control (especially Dust mite exposure)
    2. Protocol in children with strong atopic family histories (2 first degree relatives)
      1. Exclusive Breast Feeding (preferred) or hydrolyzed formula for first year
      2. No solid foods until after 6 months of age
      3. Delay nuts, shellfish, and fish until over age 4 years
      4. Breast-feeding mother avoids eggs, milk, tree nuts, peanuts, and seafood
      5. Fiocchi (2006) Ann Allergy {a 12297} Immunol 97(1):10

Atopy (C0392707)

Definition (CSP)genetic predisposition toward the development of immediate (type I) hypersensitivity reactions against common environmental antigens (atopic allergy); the most common clinical manifestation is allergic rhinitis; bronchial asthmas, atopic dermatitis and food allergy also occur.
Definition (NCI)A genetic predisposition to form IgE antibodies in response to exposure to allergens and therefore, for the development of immediate (type I) hypersensitivity and atopic conditions, such as allergic rhinitis; bronchial asthma, atopic dermatitis, and food allergy. Mutations of specific alleles on the long arm of chromosome 5 have been associated with higher levels of IL-4 and IgE and are known as IL-4 promoter polymorphisms.
ConceptsPathologic Function (T046)
EnglishAtopic allergy, Atopic diathesis, Atopic reaction, Atopic state, Atopy
Spanishatopia, diatesis atopica, estado atopico, reaccion atopica
Parent ConceptsImmediate hypersensitivity (C0020523), Immune system finding (C1291764), Hypersensitivity (C0020517)
SourcesAOD, COSTAR, CSP, MTH, NCI, OMIM, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



Navigation Tree