II. Epidemiology

  1. Accounts for one third of Nephrotic Syndrome in adults
  2. Peak Incidence 30 to 50 years old

III. Causes

  1. Idiopathic (75%)
  2. Systemic Lupus Erythematosus
  3. Hepatis B Virus Infection
  4. Drug-induced Nephrotic Syndrome
  5. Cancer

IV. Labs

  1. Urinalysis
    1. Microscopic Hematuria (variably present)

V. Labs: Pathology

  1. Thickening of glomerular basement membrane on electron microscopy
  2. IgG and C3 depositis with immunofluorescent stains

VI. Signs

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