II. Indications
III. Mechanism
- Short-Acting Anticholinergic Bronchodilator
IV. Preparations: Ipratropium Bromide
- Atrovent MDI: 2-3 puffs three to four times daily
- Atrovent Nebulization: 1 ampule in nebulization solution every 6 hours prn
V. Preparations: Combination Ipratropium with Albuterol (Combivent)
- Combivent (older CFC version)
- Will be phased out in 2013 due to CFC
- Dose: 2 puffs up to every 6 hours
- Contraindicated in soybean or peanut allergy
- Combivent Respimat
- Dose: 1 puff every 6 hours
- Does not carry the Food Allergy related contraindications of the older Combivent
VI. Adverse Effects
- Serious adverse effects
- Anaphylaxis, Angioedema or other Hypersensitivity Reaction
- Paradoxical bronchospasm or Laryngospasm
- Exacerbation of Glaucoma
- Increased cardiovascular events
- Avoid short acting Anticholinergics (Ipratropium) in comorbid cardiovascular disease
- Ogale (2010) Chest 137(1): 13-19 [PubMed]
- Singh (2008) JAMA 300(12): 1439-50 [PubMed]
- Common adverse effects
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Related Studies
| ipratropium (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| IPRATROPIUM 0.03% SPRAY | Generic | $0.80 per ml |
| IPRATROPIUM 0.06% SPRAY | Generic | $1.52 per ml |
| IPRATROPIUM BR 0.02% SOLN | Generic | $0.06 per ml |
| IPRATROPIUM-ALBUTEROL 0.5-3(2.5) MG/3 ML | Generic | $0.07 per ml |
| atrovent (on 1/1/2023 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| ATROVENT 17 MCG HFA INHALER | $34.02 per gram | |
| combivent (on 1/1/2023 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| COMBIVENT RESPIMAT 20-100 MCG | $113.86 per gram | |