Bunyaviricetes

Aka: Bunyaviricetes, Bunyaviridae, Bunyavirus, Bunyaviridae Infection, Bunyavirus Infection

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II. Pathophysiology

  1. Family Bunyaviridae (Bunyavirus) are Arboviruses (arthropod borne)
  2. Bunyaviridae are Enveloped, Helical single stranded RNA Viruses
  3. Bunyaviridae are Anti-Message Sense RNA Viruses (Negative Stranded, -ssRNA)
    1. Anti-Message sense RNA (-ssRNA) need to first be transcribed into +ssRNA
    2. RNA dependent RNA Polymerase (RNA replicase, RdRp)
      1. RdRp is an enzyme carried by the -ssRNA virus within its capsid
      2. RdRp transcribes -ssRNA into +ssRNA within the host cell
    3. Translation follows +ssRNA transcription from -ssRNA (by RdRp)
      1. As with mRNA, +ssRNA translated by host ribosomes into Protein

III. Types

  1. Genus Nairovirus
    1. Crimean–Congo hemorrhagic fever virus
  2. Genus Orthobunyavirus
    1. Bunyamwera virus
    2. California Encephalitis virus
    3. La Crosse Encephalitis virus
  3. Genus Phlebovirus
    1. Rift Valley Fever virus
    2. Toscana virus
    3. Heartland virus
  4. Hantavirus was previously included in Bunyaviridae
    1. Reclassified in the Family Hantaviridae (and the genus Orthohantavirus) as of 2018
    2. Hantavirus is also not Arthopod borne

IV. Resources

  1. Bunyaviricetes (wikipedia)
    1. https://en.wikipedia.org/wiki/Bunyaviricetes

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