III. Medications

  1. Tablets: 250 or 500 mg
  2. Suspension 125 or 250 mg/5 ml

IV. Dosing

  1. Adult
    1. Typical dosing
      1. Take 250 to 500 mg orally daily to twice daily
    2. Streptococcal Pharyngitis (second-line)
      1. Take 500 mg orally daily for 10 days
  2. Child
    1. Otitis Media
      1. GIve 15 mg/kg/dose orally twice daily
    2. Streptococcal Pharyngitis (second-line)
      1. Give 7.5 mg/kg/dose orally twice daily for 10 days
  3. Renal Dosing
    1. eGFR <30 ml/min: Give 50% of typical dose

V. Adverse Effects

  1. Allergic Reaction risk
    1. Cross reaction with Amoxicillin Allergy
  2. Gastrointestinal (oral formulations, mild)
    1. Nausea or Vomiting
    2. Diarrhea

VI. Safety

  1. Pregnancy Category B
  2. Safe in Lactation

VIII. References

  1. (2012) Presc Lett, Resource #280706, Comparison of Cephalosporins
  2. Wiseman (1993) Drugs 45(2):295-317 +PMID: 7681376 [PubMed]

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Related Studies

Cost: Medications

cefprozil (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
CEFPROZIL 125 MG/5 ML SUSP Generic $0.24 per ml
CEFPROZIL 250 MG TABLET Generic $0.44 each
CEFPROZIL 250 MG/5 ML SUSP Generic $0.32 per ml
CEFPROZIL 500 MG TABLET Generic $0.86 each