II. Indications
- See First Generation Cephalosporin
-
Generic and similar efficacy to Cephalexin
- Ease of twice daily dosing instead of four times daily
- Specific Indications
- Skin and Soft Tissue Infection
- Streptococcal Pharyngitis
- Simple Urinary Tract Infections (Acute Cystitis)
- Not indicated for Otitis Media (inadequate coverage due to resistance)
III. Mechanism
IV. Dosing
- May take with or without food
- Adult
- Give 1 g orally twice daily
- May decrease to 500 mg orally twice daily in simple UTI and Streptococcal Pharyngitis
- Child (age > 6 weeks)
- Give 30 mg/kg/day orally divided twice daily
-
Renal Dosing (Adult)
- eGFR 26 to 50 ml/min
- First dose 1 gram orally
- Then 500 mg orally every 12 hours
- eGFR 11 to 25 ml/min
- Take 500 mg every 24 hours
- eGFR <10 ml/min
- Take 500 mg every 36 hours
- eGFR 26 to 50 ml/min
V. Adverse Effects
-
Allergic Reaction
- Cross reactivity with Amoxicillin
VI. Safety
- Pregnancy Category B (All Trimesters)
- Safe in Lactation
VII. Resources
VIII. References
- (2012) Presc Lett, Resource #280706, Comparison of Cephalosporins
Images: Related links to external sites (from Bing)
Related Studies
| cefadroxil (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| CEFADROXIL 1 GM TABLET | Generic | $2.73 each |
| CEFADROXIL 250 MG/5 ML SUSP | Generic | $0.21 per ml |
| CEFADROXIL 500 MG CAPSULE | Generic | $0.27 each |
| CEFADROXIL 500 MG/5 ML SUSP | Generic | $0.30 per ml |