II. Indications
III. Contraindications
- Risk of Aspiration Pneumonia (lipoid Pneumonia)
- Malabsorption
- Age < 12 months
IV. Mechanism
- Lubricant Laxative
- Mineral Oil coats the bowel and stool with a waterproof film
- Decreases bowel absorption of water
V. Precautions
- Aspiration risk
VI. Dosing
-
General
- Give chilled in juice to maximize tolerability
- Coadminister Multivitamin daily if used chronically
- Child Dose (over 18 months of age)
- Oral Dose
- Give 1 to 3 ml/kg/day divided daily to twice daily
- Used in maintenance of bowel regimen
- Maximum: 90 ml/day
- Rectal Dose (Mineral Oil Enema)
- Disimpaction
- Give 15-30 ml per age in years up to 240 ml/day
- May repeat daily for 3-4 days
- Oral Dose
- Adult Dose (or age > 12 years)
- Low Dose
- Take 5 to 45 ml orally in the evening
- High Dose
- Take 30 to 90 ml as needed
- Low Dose
VII. Pharmacokinetics
- Onset of action
- Oral: 6 to 8 hours
- Rectal: 2 to 15 minutes
VIII. Adverse Effects
- Abdominal cramping
- Lipoid pneumonitis if aspirated
- Avoid bedtime dosing
- Anal irritation and leakage
- Vitamin malabsorption
IX. Resources
X. References
- Olson (2020) Clinical Pharmacology, Medmaster Miami, p. 94
- (2023) Management of Constipation, Presc Lett, #390108
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Related Studies
| mineral oil (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| MINERAL OIL | Generic OTC | $0.01 per ml |