II. Indications
- Peptic Ulcer Disease
- Esophageal Reflux disease
- Gastritis
- Allergic Reaction (adjunct)
III. Mechanism
- See H2 Blocker
IV. Dosing
- Adult (and age >=16 years)
- Oral dosing: 20 to 40 mg orally twice daily
- Child (40 mg/5ml oral suspension)
- Age 0-3 months
- Dose: 0.5 mg/kg/day orally daily
- Age 3 months to 16 years old
- Dose: 0.5 mg/kg orally twice daily (maximum 40 mg/dose)
- Age 0-3 months
-
Creatinine Clearance <50 ml/min
- Give at half dose
V. Efficacy
- See H2 Blocker
VI. Adverse Effects
- See H2 Blocker
VII. Safety
- Pregnancy Category B
- Unknown safety in Lactation
VIII. Resources
IX. References
- (2012) Presc Lett, 19(7): 38
- Baird (2015) Am Fam Physician 92(8): 705-14 [PubMed]