Sialoadenitis

Aka: Sialoadenitis, Sialadenitis, Salivary Gland Infection

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II. Definitions

  1. Sialoadenitis
    1. Inflammation or infection of Salivary Gland or duct
  2. Sialadenosis
    1. Autoimmune Neuropathy induced Salivary Gland localized hypertrophy of the acinar component
    2. Associated with Alcoholism, Diabetes Mellitus, Bulimia Nervosa, Malnutrition

III. Causes: Inflammatory Sialoadenitis

  1. Suppurative Sialoadenitis
    1. Acute Suppurative Sialoadenitis (Bacterial)
    2. Chronic Suppurative Sialadenitis (rare)
  2. Non-suppurative Sialoadenitis
    1. Acute
      1. Acute Nonsuppurative Sialoadenitis (Viral, esp. Mumps)
      2. Neonatal Sialadenitis
    2. Chronic or recurrent
      1. Juvenile Recurrent Parotitis (age 3 to 6 years old)
      2. Bilateral Benign Lymphoepithelial Cysts of Parotid Glands (HIV Infection)
      3. Obstructive Sialoadenitis (chronic, recurrent episodes)
      4. Systemic Autoimmune Conditions with Xerostomia (e.g. Sjogren Syndrome)
      5. Posttreatment Sialadenitis (post-radiation, Radioactive Iodine or Anesthesia)

IV. Differential Diagnosis

  1. See Salivary Gland Enlargement

V. References

  1. Kim (2024) Am Fam Physician 109(6): 550-9 [PubMed]

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