II. Physiology

  1. Substances with odor (odorants) enter nose
  2. Nasal mucosa absorbs odorants
  3. Odorants stimulate olfactory receptors at the Cribiform Plate neuroepithelium
    1. Olfactory receptors regenerate every 8 to 10 days
    2. Followed by 5 days of cilia maturation
  4. Smell-related signals pass via the Olfactory Bulb to the olfactory cerebral cortex

III. Anatomy

  1. Olfactory Nerve and Olfactory Bulb (Cranial Nerve 1)
    1. Primary transmission of Smell Sensation
  2. Trigeminal Nerve (Cranial Nerve 5) - Ophthalmic and Maxillary Divisions
    1. Influence Temperature, irritation and sharpness Sensations

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