II. Indications

  1. Lip enhancement
  2. Facial Wrinkles and folds in lower two thirds of face
    1. Nosolabial folds (old FDA approved use)
    2. Oral commissures
    3. Marionette lines (long vertical lines around the chin)

III. Mechanism

  1. Injectable substances that increase soft-tissue volume for 3-24 months

IV. Dosing

  1. Injection of 1-2 ml into Dermis
  2. One treatment per 3 to 24 months (depending on filler injected)

V. Preparations

  1. Collagen Filler (original filler introduced in the 1980s)
    1. Cosmoplast (Allergan Inc) lasts 3-4 months
  2. Hyaluronic Acid Filler
    1. Restylane and Perlane (Medicis Aesthetics) each last 6-9 months
    2. Juvederm (Allergan Inc) lasts 9-12 months
  3. Calcium Hydroxylapatite Filler
    1. Radiesse (Bioform Medical Inc) lasts 12-18 months
  4. Poly-L-lactic Acid Filler
    1. Sculptra (Dermik Lab) lasts 12-24 months

VI. Advantages

  1. Results are immediate

VII. Disadvantages

  1. Swelling and Bruising after the procedure
  2. Very operator dependent with the best outcomes with the most experienced clinicians

Images: Related links to external sites (from Bing)

Related Studies