II. Indications
- Lice (second-line treatment)
III. Contraindications
- Avoid under age 4 years old
IV. Mechanism
- Neurotoxic to lice
V. Medications
- Topical Suspension 0.9%
VI. Dosing
- Apply to dry hair, leave on for 10 minutes and rinse
- Single application is effective (but may repeat in 9-10 days if lice are still present)
- Expensive ($200-280 per bottle in 2019)
VII. Efficacy
- Lice eradication rate (85%) is twice that of Permethrin
- Best efficacy is with nit combing
- Stough (2009) Pediatrics 124(3): e389-95 [PubMed]
VIII. Safety
- Pregnancy Category B
- Unknown safety in Lactation
IX. Resources
- Spinosad topical suspension (DailyMed)
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Related Studies
| natroba (on 4/20/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| NATROBA 0.9% TOPICAL SUSP | $2.20 per ml | |