II. Indications

  1. Resistant Head Lice

III. Contraindications

  1. Infants

IV. Mechanism

V. Precautions

  1. Flammable - keep away from flame or heat source (e.g. hair dryer)
  2. Keep lotion away from eyes
  3. Not recommended for infants

VI. Medications

  1. Malathion 0.5% in Isopropanol 78% (Ovide Lotion)

VII. Dosing: Head Lice (adults and children age >6 years)

  1. Apply lotion to dry hair until hair and scalp is wet and allow hair to air dry
  2. Wash hair after 8 to 12 hours
  3. Remove nits with fine-tooth comb
  4. Re-treat in 7 to 9 days (if needed)
  5. Do NOT blow dry hair (flammable)

VIII. Adverse Effects

  1. Stinging and irritation secondary to Alcohol base
  2. Considered safe for topical use in children and adults (but avoid in infants)
    1. Little if any systemic absorption at this dose

IX. Safety

  1. Pregnancy Category B
  2. Unknown Safety in Lactation

X. Efficacy

  1. Highly pediculicidal (kills lice)
  2. Highly ovicidal (kills eggs)
  3. Offers residual protection by binding hair
  4. Resistance has been reported

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Related Studies

Cost: Medications

malathion (on 7/20/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
MALATHION 0.5% LOTION Generic $3.71 per ml