II. Pathophysiology
- Variant of Dermal Nevus (mole)
- Benign overgrowth of epidermal cells
- Recurrent inflammatory changes resulting in Eczematous or Psoriasis-like changes
- Lesions follow lines of normal Embryologic skin cell migration (blaschko lines)
- Likely result from somatic mutations with genetic mosaicism
III. Epidemiology
- Presents in newborns and young children
- Female gender predominance
- Primarily sporadic but may be genetic
IV. Findings
- Unilateral, scaly, pruritic Plaques or Papules in a linear pattern
- Red, brown or purple lesions (or may be Skin Colored)
V. Management
- No definitive treatment and often refractory to therapy
- Potent Topical Corticosteroids (e.g. Fluocinonide ointment)
- Tacrolimus
- Surgical excision
- Carbon dioxide laser therapy