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Base ExcessAka: Base Deficit

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  1. Definition
    1. Base that must be added to Restore a normal pH
  2. Normal
    1. Range: -2 to +2 meq/L
  3. Calculation
    1. Base Excess = (Actual_pH - Predicted_pH) * 67
    2. Calculate predicted pH based on PaCO2 (see Blood Gas)
  4. Interpretation
    1. Positive (Base Excess)
      1. Metabolic Alkalosis
    2. Negative (Base Deficit)
      1. Metabolic Acidosis
  5. Application: Neonatology
    1. Severe Acidosis (Base Excess < -10)
      1. Calculate Total Body Bicarbonate deficit
        1. Deficit = (Base Deficit) x (Weight in kg) x 0.3
      2. Administer 25% of bicarbonate deficit (~1 meq/kg)

Base excess measurement (C0201985)

ConceptsLaboratory Procedure (T059)
EnglishActual base excess, Base excess, Base excess - observation, Base excess measurement, BE - Base excess
Spanishexceso de base, medicion del exceso de base
Parent ConceptsBiochemical test (C0430027), Evaluation of acid-base balance (C0699847)
SourcesLNC, MTH, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)


Base deficit (C0347530)

ConceptsFinding (T033)
EnglishBase deficit, Hypobasemia, Negative base excess
Spanishdeficit de base, hipobasemia
Parent ConceptsAdditional biochemical finding (C0560218)
SourcesLNC, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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