III. Indication

  1. Insomnia
  2. Consider for early awakening in middle of night

IV. Pharmacokinetics

  1. Half-Life: 1 hour
  2. Peak Onset: 30 minutes
  3. Duration
    1. Typically 4 hours, but may be as long as 6-8 hour
  4. Metabolized by CYP450 3A4

V. Dosing

  1. Start: 5-10 mg orally at bedtime
  2. Elderly: 5 mg orally at bedtime
  3. Maximum: 20 mg orally at bedtime

VI. Adverse Effects

  1. See Nonbenzodiazepine Hypnotic Agent for common effects
  2. Altered color Perception

VII. Advantages

  1. See Nonbenzodiazepine Hypnotic Agent
  2. Effective in middle of night awakening
    1. Can take mid-way through sleep period

Images: Related links to external sites (from Bing)

Related Studies

Cost: Medications

zaleplon (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
ZALEPLON 10 MG CAPSULE Generic $0.16 each
ZALEPLON 5 MG CAPSULE Generic $0.18 each