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Estazolam

Aka: Estazolam, Prosom
  1. See Also
    1. Benzodiazepine
  2. Class
    1. Medium acting Benzodiazepine
  3. Indication
    1. Insomnia
  4. Background
    1. Weekly Cost: $6
  5. Pharmacokinetics
    1. Onset: 20 minutes
    2. Duration: 6-8 hours
    3. Half-Life: 10-24 hours
  6. Dosing
    1. Dose: 1-2 mg PO qhs

Estazolam (C0014892)

Definition (MSH) A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than DIAZEPAM or NITRAZEPAM.
Definition (NCI) A triazolo-benzodiazepine with anxiolytic, anticonvulsant, hypnotic, and muscle relaxant properties. Estazolam binds to the gamma-aminobutyric acid (GABA) receptor at a site distinct from the inhibitory neurotransmitter GABA binding site in the limbic system of the central nervous system (CNS). This binding leads to an opening of the chloride channels, which allows the flow of chloride ions into the neuron, hyperpolarizes the neuronal membrane, inhibits neuronal firing, and leads to a decrease in neuronal excitability.
Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH D004949
SnomedCT 96235001, 371364001
English Estazolam, 4H-(1,2,4)Triazolo(4,3-a)(1,4)benzodiazepine, 8-chloro-6-phenyl-, 8-Chloro-6-phenyl-4H-(1,2,4)triazolo-(4,3-a)(1,4)benzodiazepine, estazolam, sedatives estazolam, estazolam (medication), ESTAZOLAM, Estazolam [Chemical/Ingredient], Estazolam (substance), Estazolam product (product), Estazolam product
Swedish Estazolam
Czech estazolam
Finnish Estatsolaami
Russian ESTAZOLAM, ЭСТАЗОЛАМ
Japanese エスタゾラム
Spanish estazolam, producto (producto), estazolam (producto), estazolam, producto, estazolam (sustancia), estazolam, Estazolam
Polish Estazolam
French Estazolam
German Estazolam
Italian Estazolam
Portuguese Estazolam
Sources
Derived from the NIH UMLS (Unified Medical Language System)


ProSom (C0722865)

Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH D004949
English Prosom, prosom, ProSom, Abbott Brand of Estazolam
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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