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EstazolamAka: Prosom
- See Also
- Class
- Medium acting Benzodiazepine
- Indication
- Background
- Weekly Cost: $6
- Pharmacokinetics
- Onset: 20 minutes
- Duration: 6-8 hours
- Half-Life: 10-24 hours
- Dosing
- Dose: 1-2 mg PO qhs
Estazolam (C0014892) | |
|---|---|
| Definition (MSH) | A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than DIAZEPAM or NITRAZEPAM. |
| Definition (NCI) | A triazolo-benzodiazepine with anxiolytic, anticonvulsant, hypnotic, and muscle relaxant properties. Estazolam binds to the gamma-aminobutyric acid (GABA) receptor at a site distinct from the inhibitory neurotransmitter GABA binding site in the limbic system of the central nervous system (CNS). This binding leads to an opening of the chloride channels, which allows the flow of chloride ions into the neuron, hyperpolarizes the neuronal membrane, inhibits neuronal firing, and leads to a decrease in neuronal excitability. |
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | D004949 |
| English | Estazolam, ESTAZOLAM PREPARATION, Estazolam product |
| Spanish | estazolam |
| Parent Concepts | Benzodiazepines (C0005064), [CN302] BENZODIAZEPINE DERIVATIVE, SEDATIVES/HYPNOTICS (C0973503), Benzodiazepine sedative (C0360114) |
| Sources | LNC, MSH, MTHSPL, NCI, NDFRT, RXNORM, SCTSPA, SNOMEDCT, VANDF Derived from the NIH UMLS (Unified Medical Language System) |
ProSom (C0722865) | |
|---|---|
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | D004949 |
| English | Abbott Brand of Estazolam, ProSom |
| Sources | MSH, NCI, RXNORM Derived from the NIH UMLS (Unified Medical Language System) |