Obstetrics Book

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Nuchal Translucency

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  1. See Also
    1. Antenatal Screening
  2. Definition
    1. Posterior fetal neck lucency by ultrasound
  3. Indications
    1. Early Antenatal Screening for Down Syndrome and birth defects
  4. Protocol
    1. Timing: 11-13 weeks gestation
    2. Technique
      1. Ultrasound used to measure the lucency of the posterior fetal neck
      2. Measurement requires additional special training and certification
  5. Efficacy: Down Syndrome detection
    1. Test Sensitivity: 70%
    2. Test Specificity: >95%
  6. Differential Diagnosis: Increased Nuchal Translucency
    1. Down Syndrome and other genetic syndromes
    2. Major congenital heart defect
    3. Great vessel defect
    4. Fetal malformations, dysplasias, deformations and disruptions
    5. False positives (nuchal translucency increases 15-20% per week in normal pregnancies)
  7. References
    1. Anderson (2009) Am Fam Physician 79(2):117
    2. Makrydimas (2005) Am J Obstet Gynecol 192(1):89
    3. Salvedt (2005) Ultrasound Obstet Gynecol 25(6):537
    4. Souka (2005) Am J Obstet Gynecol 192(4):1005

Nuchal Translucency Measurement (C1449832)

Definition (MSH)A prenatal ultrasonic measurement of the thickness or translucent area below the SKIN in the back of the fetal NECK, or nape of the neck, during the first 11-14 weeks of gestation (PREGNANCY TRIMESTER, FIRST). Abnormal thickness or nuchal translucent measurements resulting from fluid collection, is associated with increased risks of CHROMOSOME ABNORMALITIES. (Nicolaides et al., 1992)
ConceptsDiagnostic Procedure (T060)
MSHD048208
EnglishNuchal Translucency Measurement, Nuchal Translucency Measurements, Nuchal Translucency Screening, Nuchal Translucency Screenings
Parent ConceptsUltrasonography, Prenatal (C0080265)
SourcesMSH
Derived from the NIH UMLS (Unified Medical Language System)



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