II. Indications

  1. Included in Triple Screen

III. Physiology

  1. Normally produced at low levels by ovaries
  2. Elevated in pregnancy
    1. Produced by placenta
    2. Precursors supplied by fetus
      1. Fetal Adrenal Glands
      2. Fetal liver

IV. Increased Unconjugated Estriol

  1. Increases throughout normal pregnancy

V. Decreased Unconjugated Estriol

  1. Trisomy 21 (Down Syndrome)
  2. Trisomy 18 (Edwards Syndrome)

Images: Related links to external sites (from Bing)

Related Studies (from Trip Database) Open in New Window