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Chorioamnionitis

Aka: Chorioamnionitis, Intra-Amniotic Infection

See Also
1. Group B Streptococcus Prophylaxis
Risk Factors
1. Prolonged Rupture of Membranes
2. Multiple intrapartum vaginal exams
3. Internal monitoring
4. Chorioamnionitis in prior pregnancy (2 fold risk)
  1. Laibl (2006) Obstet Gynecol 108: 1493-7
Signs
1. Maternal Fever with temperature > 100.7 F
2. No obvious source other than Uterus
3. Associated findings suggestive of Chorioamnionitis
  1. Fetal Tachycardia
  2. Maternal Tachycardia
  3. Abdominal tenderness
  4. Foul smelling amniotic fluid
Labs
1. Complete Blood Count
  1. Leukocytosis
2. Amniotic fluid culture
Differential Diagnosis
Management
1. Chorioamnionitis is not an indication for cesarean
2. See Chorioamnionitis Antibiotic Management
Course
1. Fetal outcome improves with
  1. Antibiotics
  2. Defervescence
Complications
1. Neonatal Sepsis
2. Maternal Sepsis
3. Postpartum Hemorrhage
4. Labor Dystocia

Chorioamnionitis (C0008495)
Definition (NCI)	Inflammation of the fetal sac membranes.
Definition (MSH)	INFLAMMATION of the placental membranes (CHORION; AMNION) and connected tissues such as fetal BLOOD VESSELS and UMBILICAL CORD. It is often associated with intrauterine ascending infections during PREGNANCY.
Concepts	Pathologic Function (T046)
MSH	D002821
ICD10	O41.1290, O41.12
SnomedCT	267263003, 11612004, 199675000
English	Amnionitis, Chorioamnionitides, CHORIOAMNIONITIS, Chorioamnionitis, unspecified trimester, not applicable or unspecified, Chorioamnionitis [Disease/Finding], Chorioamnionitis, amnioniti, amnionitis, Membranitis, Chorioamnionitis (disorder), chorioamnionitis, membranitis, Chorioamnionitis [Ambiguous]
Japanese	絨毛膜羊膜炎, ｼﾞｭｳﾓｳﾏｸﾖｳﾏｸｴﾝ
Swedish	Fosterhinneinflammation
Czech	chorioamnionitida, Chorioamnionitida
Spanish	Membranitis, Chorioamnionitis, Chorioamnionitis [Ambiguous], corioamnionitis (trastorno), corioamnionitis, membranitis, Corioamnionitis
Finnish	Korioamniitti
Russian	AMNIONIT, KHORIOAMNIONIT, АМНИОНИТ, ХОРИОАМНИОНИТ
Croatian	KORIOAMNIONITIS
Polish	Zapalenie błon płodowych i łożyska, Zapalenie błon płodowych, Zakażenie wewnątrzowodniowe
Hungarian	Chorioamnionitis
Dutch	chorioamnionitis, Amnionitis, chorio-, Chorioamnionitis
French	Chorioamniotite, Chorio-amniotite
German	Chorioamnionitis
Italian	Corioamnionite
Portuguese	Corioamnionite
Sources	Derived from the NIH UMLS (Unified Medical Language System)