II. Risk Factors

  1. Prolonged Rupture of Membranes
  2. Multiple intrapartum vaginal exams
  3. Internal monitoring
  4. Chorioamnionitis in prior pregnancy (2 fold risk)
    1. Laibl (2006) Obstet Gynecol 108: 1493-7 [PubMed]

III. Signs

  1. Maternal Fever with Temperature > 100.7 F
  2. No obvious source other than Uterus
  3. Associated findings suggestive of Chorioamnionitis
    1. Fetal Tachycardia
    2. Maternal Tachycardia
    3. Abdominal tenderness
    4. Foul smelling amniotic fluid

IV. Labs

  1. Complete Blood Count
    1. Leukocytosis
  2. Amniotic fluid culture

V. Differential Diagnosis

VI. Management

  1. Chorioamnionitis is not an indication for cesarean
  2. See Chorioamnionitis Antibiotic Management

VII. Course

  1. Fetal outcome improves with
    1. Antibiotics
    2. Defervescence

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Ontology: Chorioamnionitis (C0008495)

Definition (NCI) A morphologic finding indicating inflammation of the fetal sac membranes. It is characterized by neutrophilic infiltration of the amnion and chorion.
Definition (MSH) INFLAMMATION of the placental membranes (CHORION; AMNION) and connected tissues such as fetal BLOOD VESSELS and UMBILICAL CORD. It is often associated with intrauterine ascending infections during PREGNANCY.
Concepts Pathologic Function (T046)
MSH D002821
ICD10 O41.1290 , O41.12
SnomedCT 199675000, 267263003, 11612004
English Chorioamnionitides, Amnionitis, Chorioamnionitis, unspecified trimester, not applicable or unspecified, Chorioamnionitis [Disease/Finding], Chorioamnionitis, amnionitis, Chorioamnionitis, unsp trimester, not applicable or unsp, chorioamnionitis, chorioamnionitis (diagnosis), CHORIOAMNIONITIS, Membranitis, Chorioamnionitis (disorder), membranitis, Chorioamnionitis [Ambiguous]
Swedish Fosterhinneinflammation
Czech chorioamnionitida, Chorioamnionitida
Finnish Korioamniitti
Russian AMNIONIT, KHORIOAMNIONIT, АМНИОНИТ, ХОРИОАМНИОНИТ
Croatian KORIOAMNIONITIS
Polish Zapalenie błon płodowych i łożyska, Zapalenie błon płodowych, Zakażenie wewnątrzowodniowe
Norwegian Betennelse i fosterhinne og morkake, Korioamnionitt
Dutch chorioamnionitis, Amnionitis, chorio-, Chorioamnionitis
Hungarian Chorioamnionitis
Japanese 絨毛膜羊膜炎, ジュウモウマクヨウマクエン
Spanish corioamnionitis (trastorno), corioamnionitis, membranitis, Corioamnionitis
French Chorioamniotite, Chorio-amniotite
German Chorioamnionitis
Italian Corioamnionite
Portuguese Corioamnionite