Pulmonology Book

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Nebulized Lidocaine

Aka: Nebulized Lidocaine
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  1. Indications
    1. Asthma Exacerbation with refractory cough
  2. Precautions
    1. Off-label use
    2. Lidocaine can have serious toxicity
    3. Dosing is not standardized, and although appears safe and effective, there is a paucity of literature
  3. Dosing
    1. General
      1. Use Lidocaine Solution (2% or 4%)
      2. Dilute in 5 cc Normal Saline
      3. Maximum: 3 mg/kg Lidocaine
    2. Adults
      1. Lidocaine 4%, 3 ml in normal saline nebulized 3-4 times daily
      2. Hunt (2004) J Allergy Clin Immunol 113(5):853-9.
    3. Children
      1. Lidocaine 2%, 0.8 mg/kg/dose to 2.5 mg/kg/dose in normal saline nebulized 3-4 times daily
      2. Decco (1999) Ann Allergy Asthma Immunol 82(1):29-32.

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