Pulmonology Book

Approach

  • Asbestos Exposure

Asbestosis

Pleural

http://www.fpnotebook.com/

Asbestos Exposure

Aka: Asbestos Exposure, Asbestos
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  1. See Also
    1. Asbestosis
    2. Pleural Plaques
    3. Mesothelioma
  2. Background
    1. Smallest, naturally occurring fiber
    2. Asbestos used industrially until 1970s in U.S.
      1. Aeronautics materials
      2. Electrical product lining
      3. Shipping materials
      4. Brake linings and clutch pads
      5. Building materials
    3. Asbestos Exposures continue today
      1. Building demolition and Asbestos removal
      2. Asbestos or vermiculite mines
    4. Asbestos risks have been known for >100 years
      1. First linked to lung disease in 1890
      2. Exposure legislation in United Kingdom as of 1931
      3. Exposure legislation in United States as of 1971
  3. Pathophysiology
    1. Exposure occurs with Asbestos fiber inhalation
    2. Consequences of Asbestos Exposure delayed 10-40 years
  4. Complications
    1. Asbestosis (fibrotic lung disease)
    2. Mesothelioma
    3. Pleural Plaques
    4. Pleural Effusions
      1. Unilateral, exudative Pleural Effusions
      2. Asbestos-related is diagnosis of exclusion
        1. Consider Tuberculosis, Mesothelioma, Lung Cancer
    5. Lung Cancer
      1. Tobacco use increases risk dramatically
      2. Asbestos-related Lung Cancer deaths: >2000/year U.S.
      3. Observe for non-calcified lesions on XRay
      4. Types
        1. Non-small cell and small cell
        2. Mesothelioma (appears same as Lung Cancer on XRay)
  5. Risk factors: Asbestos related disease
    1. Several months of significant Asbestos Exposure and
    2. Clinical presentation at least 10 years later
  6. Management
    1. No specific management
    2. Tobacco Cessation
  7. Monitoring
    1. ATS recommends repeat Chest XRay every 3-5 years
  8. Resources
    1. Asbestos.Net
      1. http://www.asbestos.net/
  9. References
    1. O'Reilly (2007) Am Fam Physician 75:683-90
    2. (2004) Am J Respir Crit Care Med 170:691-715

Asbestos (C0003947)

Definition (MEDLINEPLUS)

Asbestos is the name of a group of minerals with long, thin fibers. It was once used widely as insulation. It also occurs in the environment. Asbestos fibers are so small you can't see them. Disturbing asbestos can cause fibers to float in the air. When this happens, they are easy to inhale. You breathe out most fibers, but some become lodged in the lungs. Over time, they can build up in the lungs, causing scarring and inflammation. This can eventually affect breathing and lead to disease, such as

  • Asbestosis, or scarring of the lungs that makes it hard to breathe
  • Mesothelioma, a rare cancer that affects the lining of the lungs or abdomen
  • Lung cancer

Lung diseases associated with asbestos usually develop over many years. Smoking cigarettes increases the risk.

Agency for Toxic Substances and Disease Registry

Definition (NCI) A group of minerals that take the form of tiny fibers. Asbestos has been used as insulation against heat and fire in buildings. Loose asbestos fibers breathed into the lungs can cause several serious diseases, including lung cancer and malignant mesothelioma (cancer found in the lining of the lungs, chest, or abdomen). Asbestos that is swallowed may cause cancer of the gastrointestinal tract.
Definition (MSH) Asbestos. Fibrous incombustible mineral composed of magnesium and calcium silicates with or without other elements. It is relatively inert chemically and used in thermal insulation and fireproofing. Inhalation of dust causes asbestosis and later lung and gastrointestinal neoplasms.
Definition (CSP) fibrous incombustible mineral composed of magnesium and calcium silicates with or without other elements; it is relatively inert chemically and has been used in thermal insulation and fireproofing; inhalation of dust causes asbestosis and later lung and gastrointestinal neoplasms.
Definition (NCI) One of a number of fibrous magnesium and calcium silicate minerals processed for thermal insulation and fireproofing. Asbestos is considered to be an environmental carcinogen; chronic inhalation of fine asbestos dust causes pulmonary asbestosis and may induce lung neoplasms. Chronic ingestion of asbestos may induce gastrointestinal neoplasms. (NCI04)
Concepts Hazardous or Poisonous Substance (T131) , Inorganic Chemical (T197)
MSH D001194
SnomedCT 16369005
English Asbestos, Asbestos fibers, NOS, Asbestos, NOS, asbestos, Asbestos [Chemical/Ingredient], asbestos fiber, asbesto, asbestos fibers, Asbestos (substance), Asbestos fibers, Asbestos fibres
Swedish Asbest
Czech azbest, osinek
Finnish Asbesti
French Asbeste, Amiante
Russian ASBEST, АСБЕСТ
Croatian AZBEST
Spanish Amiantos, Amianto, Asbestos, Asbesto, amianto (sustancia), amianto, asbestos, fibras de amianto, fibras de asbestos
Portuguese Asbesto, Asbestos, Amiantos, Amianto
Polish Azbest
German Asbest
Italian Asbesto
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Asbestos exposure (C0003948)

Concepts Injury or Poisoning (T037)
English ASBESTOS EXPOSURE, Asbestos Exposure, asbestos exposure, EXPOSURE ASBESTOS, Asbestos exposure
Dutch blootstelling aan asbest
German Asbestexposition
Italian Esposizione ad asbesto
Portuguese Exposição a asbesto
Spanish Exposición a asbesto
French Exposition à l'asbestos
Japanese アスベストバクロ, アスベスト曝露
Czech Vystavení účinkům azbestu
Hungarian Azbeszt expozíció
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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