Infectious Disease Book

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ClindamycinAka: Cleocin

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  1. Indications
    1. Peritonitis
    2. Anaerobic Bacteria infection
  2. Activity spectrum
    1. Gram Positive Bacteria
    2. No activity against Gram Negative Bacteria
  3. Adverse Effects
    1. Pseudomembranous colitis
  4. Directions
    1. May take with or without food
  5. Dosing: Child
    1. Preterm Infant
      1. Intravenous: 15 mg/kg/day IV divided tid
    2. Term Infant and Child
      1. Intravenous: 20-40 mg/kg/day IV divided q6-8 hours
      2. Oral: 8-20 mg/kg/day divided tid to qid
  6. Dosing: Adult
    1. Oral: 150-450 mg PO qid
    2. Intramuscular: up to 600 mg PO q8 hours
    3. Intravenous: 600 to 900 mg IV q8 hours

Clindamycin (C0008947)

Definition (MSH)An antibacterial agent that is a semisynthetic analog of LINCOMYCIN.
Definition (NCI)A semisynthetic broad spectrum antibiotic produced by chemical modification of the parent compound lincomycin. Clindamycin dissociates peptidyl-tRNA from the bacterial ribosome, thereby disrupting bacterial protein synthesis. (NCI04)
ConceptsCarbohydrate (T118) , Antibiotic (T195)
MSHD002981
English7 Chloro 7 deoxylincomycin, 7-Chloro-7-deoxylincomycin, Chlolincocin, Chlorlincocin, Clindamicin, Clindamycin, CLINDAMYCIN PREPARATION, Clindamycin product
Spanishclindamicina, producto con clindamicina
Parent ConceptsLincomycin (C0023726), Antibiotics (C0003232), Protein Synthesis Inhibitors (C0033671), Lincomycin Antibacterials (C0973480), [DE752] ANTIACNE AGENTS, TOPICAL (C0973530), [GU300] ANTI-INFECTIVES, VAGINAL (C0973559), Antibiotics, Aminoglycoside (C0003233), lincosamide (C0065002), Lincomycin and derivatives (C0360333), Topical form clindamycin (C0360339), Duplicate concept (C1274013)
SourcesCSP, LCH, LNC, MSH, MTHSPL, NCI, NDFRT, PDQ, RXNORM, SCTSPA, SNOMEDCT, USPMG, VANDF
Derived from the NIH UMLS (Unified Medical Language System)


Cleocin (C0699673)

ConceptsCarbohydrate (T118) , Antibiotic (T195)
MSHD002981
EnglishCleocin
SourcesMSH, NCI, RXNORM
Derived from the NIH UMLS (Unified Medical Language System)



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