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Endometrial Biopsy Interpretation

See Also
1. Endometrial Biopsy
Indications
1. Abnormal Uterine Bleeding
Biopsy Results: Normal
1. Atrophic endometrium
2. Proliferative endometrium
3. Secretory endometrium
Biopsy Results: Abnormal
1. Endometrial Cancer
2. Endometrial Hyperplasia
  1. Cystic hyperplasia (rarely progresses to cancer)
    1. No treatment necessary
  2. Adenomatous hyperplasia (10% progresses to cancer)
    1. Intermittent or continuous Progestin
    2. Repeat biopsy in 3 to 6 months
  3. Atypical Adenomatous hyperplasia (25-50% progress)
    1. No future pregnancy planned
      1. Hysterectomy
    2. Future Fertility desired
      1. Consult with gynecology due to high risk
      2. High dose continuous Progestin
      3. Resample every 6 months

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This page was written by Scott Moses, MD. This page was last revised before 5/10/08, prior to consistent tracking of revision date. This page was last published on 6/1/2008. Please send comments and questions to the editor. Contact information may be found on the page About the Family Practice Notebook. These pages are best viewed with Microsoft Internet Explorer 6.0.