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SimethiconeAka: Gas-X, Mylicon, Phazyme
- Indications
- Eructation
- Flatulence
- Dose
- Adults: 40-125 mg po qid
- Infants: 0.3 ml PO qid prn
- Pharmacokinetics
- Not absorbed
- Efficacy
- Several controlled clinical trials have been performed
- No evidence that simethicone is better than Placebo
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| Definition (MSH) | A poly(dimethylsiloxane) which is a polymer of 200-350 units of dimethylsiloxane, along with added SILICA GEL. It is used as an antiflatulent, surfactant, and ointment base. |
| Definition (NCI) | A mixture of polydimethylsiloxanes with antifoaming and anti-bloating effects. Simethicone reduces the surface tension of gas bubbles causing them to coalesce into larger bubbles that can be passed more easily by belching or flatulence. |
| Concepts | Organic Chemical (T109)
, Pharmacologic Substance (T121)
, Biomedical or Dental Material (T122)
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| English | Activated dimethicone, Activated methylpolysiloxane, Simethicone, SIMETHICONE PREPARATION, Simeticone |
| Spanish | dimeticona, dimeticona activada, metilpolisiloxano activado, simeticona |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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