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Sulfa-free 5-Aminosalacylic acid
Aka: Sulfa-free 5-Aminosalacylic acid, Sulfa-free 5-ASA, Mesalamine, Asacol, Pentasa, Rowasa, Lialda- Mechanism
- Indications
- General
- Rectal forms are preferred for Proctitis
- Use oral and rectal forms combined for better results where pancolitis is present
- Dosing
- Oral
- Asacol 800 mg PO tid
- Pentasa 1000 mg PO qid
- Lialda 1200 mg, 2-4 tabs PO once daily
- Apriso 1.5 grams orally every morning
- Rectal (Provides high distal colon concentrations)
- Rowasa 500 mg suppository PR bid
- Rowasa 4g in 60 ml Enema qhs
- Canasa 1000 mg rectal suppository at bedtime
- Oral
| Medication Costs | ||
|---|---|---|
| Mesalamine (on 2/9/2012 at DrugStore.com) | ||
| Mesalamine 4gm Enema 60ml Bottle | #1 for $35.99 | ($35.99/unit) |
| Asacol (on 2/9/2012 at DrugStore.com) | ||
| Asacol 400mg Enteric Coated Tabs | #30 for $64.99 | ($2.17/unit) |
| Asacol HD (on 2/9/2012 at DrugStore.com) | ||
| Asacol HD 800mg Enteric Coated Tabs | #90 for $390.01 | ($4.33/unit) |
| Pentasa (on 2/9/2012 at DrugStore.com) | ||
| Pentasa 250mg Capsules | #240 for $332.01 | ($1.38/unit) |
| Pentasa 500mg Capsules | #30 for $90.99 | ($3.03/unit) |
| Lialda (on 2/9/2012 at DrugStore.com) | ||
| Lialda 1.2gm Enteric Coated Tabs | #120 for $766.97 | ($6.39/unit) |
| FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. | ||
Lialda (C1873792) |
|
|---|---|
| Concepts | Amino Acid, Peptide, or Protein (T116) , Pharmacologic Substance (T121) |
| English | Lialda |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Rowasa (C0699623) |
|
|---|---|
| Concepts | Amino Acid, Peptide, or Protein (T116) , Pharmacologic Substance (T121) |
| MSH | D019804 |
| English | rowasa, Rowasa, Solvay Brand of Mesalamine |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Asacol (C0678172) |
|
|---|---|
| Concepts | Amino Acid, Peptide, or Protein (T116) , Pharmacologic Substance (T121) |
| MSH | D019804 |
| English | asacol, Asacol, Byk Brand of Mesalamine, Procter & Gamble Brand of Mesalamine |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Pentasa (C0678171) |
|
|---|---|
| Concepts | Amino Acid, Peptide, or Protein (T116) , Pharmacologic Substance (T121) |
| MSH | D019804 |
| English | pentasa, Pentasa, Allphar Brand of Mesalamine, Ferring Brand of Mesalamine, Yamanouchi Brand of Mesalamine |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
mesalamine (C0127615) |
|
|---|---|
| Definition (MSH) | An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed) |
| Definition (NCI) | An agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and prostaglandin production. Following rectal or oral administration, only a small amount of mesalamine is absorbed; the remainder, acting topically, reduces bowel inflammation, diarrhea, rectal bleeding and stomach pain. (NCI04) |
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | D019804 |
| SnomedCT | 387501005, 346319009, 86977007, 317439005, 363629007 |
| English | Mesalamine, Mesalazine duplicate deleted, 5 Aminosalicylic Acid, 5-Aminosalicylic Acid, 5-Amino-2-hydroxybenzoic Acid, m Aminosalicylic Acid, m-Aminosalicylic Acid, meta Aminosalicylic Acid, meta-Aminosalicylic Acid, mesalamine (medication), 5-aminosalicylic acid (substance), mesalamine (Rowasa), MESALAMINE, Mesalamine [Chemical/Ingredient], 5 asa, m-aminosalicylic acid, mesalazine, 5-asa, asa 5, 5-ASA, 5-Aminosalicylic acid, Fisalamine, m-Aminosalicylic acid, Mesalamine (substance), 5-aminosalicylic acid, 5ASA - Mesalazine, Mesalamine (product), Mesalamine product, Mesalamine product (product), Mesalamine product (substance), Mesalazine duplicate deleted (product), Mesalazine duplicate deleted (substance), Mesalazine, mesalamine |
| Swedish | Mesalamin |
| Czech | mesalazin, mesalamin |
| Spanish | 5-aminosalicylic acid, mesalazina, mesalamina, mesalazina (sustancia), 5-ASA, mesalazina (producto), mesalamina (producto), mesalamina (sustancia), mesalazina (duplicado borrado) (producto), mesalazina (duplicado borrado), fisalamina, mesalamina, producto (producto), mesalamina, producto, ácido 5-aminosalicílico, ácido m-aminosalicílico, Mesalacina, Mesalamina |
| Finnish | Mesalatsiini |
| Russian | MEZALAMIN, MEZALAZIN, 5-AMINOSALITSILAT, 5-АМИНОСАЛИЦИЛАТ, МЕЗАЛАЗИН, МЕЗАЛАМИН |
| Japanese | メサラミン, ペンタサ, 5-アミノサリチル酸, フィサラミン(メサラジン), メサラジン |
| French | Acide 5-amino-salicylique, Acide 5-aminosalicylique, Mésalazine, Fisalamine, Mésalamine |
| Polish | Mesalamina, Mesalazyna, 5-aminosalicylan |
| German | Mesalamine |
| Italian | Mesalamina |
| Portuguese | Mesalamina, Mesalazina |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |