II. Indications

III. Protocol: Subcutaneous InsulinLispro

  1. Initial dose: 0.3 units/kg
  2. Next: 0.1 units/kg/hour until Hyperglycemia corrects
  3. Next: 0.05 units/kg/hour until DKA resolves
  4. Coadminister fluids as per Diabetic Ketoacidosis
  5. Discontinue hourly dosing when Glucose 150-200

IV. Precautions

  1. Correct Hypokalemia prior to Insulin Dosing
  2. Fluid administration is central to DKA treatment

V. Monitoring

  1. Blood Glucose every 30 minutes to 1 hour

VI. Advantage over Insulin Infusion

  1. May be monitored on regular medical ward (non-ICU)
  2. Reduced cost by 39% compared with infusion

VII. Safety and efficacy

  1. As effective and safe as Insulin Infusion

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