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GlucagonAka: GlucaGen
- Indications
- Hypoglycemia with difficult Intravenous Access
- Neonatal Hypoglycemia
- Pharmacokinetics
- Onset of action: 5 to 20 minutes
- Dosing
- Adult: 1 mg IV, IM or SC
- Pediatric
- Standard dose: 30 ug/kg IM
- Newborn of diabetic mother: 300 ug/kg IM
- Maximum dose: 1 mg
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| Definition (MSH) | A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511) |
| Definition (CSP) | pancreatic hormone secreted by the alpha cells of the pancreatic islets; a 29-amino acid straight chain polypeptide that plays an important role in regulation of blood glucose concentration, ketone metabolism, and several other biochemical and physiological processes. |
| Definition (NCI) | A pancreatic hormone consisting of 29 amino acids that causes increases in blood sugar levels by stimulating hepatic glycogenolysis and gluconeogenesis. |
| Concepts | Amino Acid, Peptide, or Protein (T116)
, Pharmacologic Substance (T121)
, Neuroreactive Substance or Biogenic Amine (T124)
, Hormone (T125)
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| English | Antidiabetic Hormone, GCG, Glucagon, GLUCAGON PREPARATION, Glucagon product, Glukagon, HG Factor, Hyperglycemic Glycogenolytic Factor |
| Spanish | glucagón, glucagon, preparado con glucagón, preparado con glucagon, preparado de glucagón, preparado de glucagon |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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