Emergency Medicine Book

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Syrup of IpecacAka: Ipecac

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  1. Mechanism
    1. Induces Vomiting
  2. Indications: Gastric Decontamination in poison ingestion
    1. Not recommended for routine use in poison ingestion
      1. Does not improve outcome or reduce ER referral
      2. Bond (2003) Pediatrics 112:1061
    2. If administered, use within 60 minutes of ingestion
    3. Very effective in Aspirin or Iron ingestion
    4. Home management directed by Poison control
      1. No role in the Emergency Department
  3. Contraindications
    1. Anticipation of advanced life support in next hour
    2. Children under age 6 months
    3. Decreased Level of Consciousness
      1. Coma
      2. Seizures
    4. Ingestions with serious aspiration risk
      1. Corrosives (acids or bases)
      2. Hydrocarbons (Petroleum products)
    5. Sharp object ingestion
    6. Third trimester of pregnancy
    7. Protracted Emesis
  4. Complications
    1. Protracted Emesis
    2. Ineffective if over 1 hour post-ingestion
    3. Delays the administration of charcoal
  5. Dose
    1. Background
      1. Follow or precede with 120 to 240 ml water
      2. Do not use in age under 6 months
      3. May repeat dose if no Emesis in 30 minutes
    2. Dose
      1. Adults: 15 to 30 ml Ipecac
      2. Child (<12 years): 15 ml Ipecac
      3. Infant (6-12 months): 5-10 ml Ipecac

Ipecac (C0022046)

Definition (MSH)A syrup made from the dried rhizomes of two different species, CEPHAELIS ipecacuanha and C. acuminata. They contain EMETINE, cephaeline, psychotrine and other ISOQUINOLINES. Ipecac syrup is used widely as an emetic acting both locally on the gastric mucosa and centrally on the chemoreceptor trigger zone.
ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
MSHD007486
EnglishIpecac, IPECAC PREPARATION, Ipecac syrup, IPECAC SYRUP PREPARATION, Ipecacuanha, Ipecacuanha syrup, Syrup of Ipecac
Spanishipecacuana, jarabe de bejuguillo, jarabe de ipecacuana
Parent ConceptsEmetics (C0013973), Plant Extracts (C0032081), Expectorants (C0015314), Alkaloids (C0002062), Ipecac (C0022046), [AD900] ANTIDOTES/DETERRENTS, OTHER (C0973464), Antidotes (C0003295), Drug allergen (C1320237)
SourcesAOD, LCH, MSH, MTH, NCI, NDFRT, RXNORM, SCTSPA, SNOMEDCT, VANDF
Derived from the NIH UMLS (Unified Medical Language System)



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