Indication
1. Assess Risk of stroke with Atrial Fibrillation
Criteria (mneumonic: CHADS)
1. Congestive Heart Failure (1 point)
  1. Relative risk of Stroke or TIA: 1.4
2. Hypertension (1 point)
  1. Relative risk of Stroke or TIA: 1.6
3. Age over 75 years (1 point)
  1. Relative risk of Stroke or TIA: 1.4
4. Diabetes Mellitus (1 point)
  1. Relative risk of Stroke or TIA: 1.7
5. Stroke or TIA history (2 points)
  1. Mitral Stenosis or prosthetic heart valve carry similar risk and also indicate Warfarin
  2. Relative risk of Stroke or TIA: 2.5
Interpretation
1. CHADS Score >2 (CVA risk >5% per year): Warfarin with goal INR 2.0 to 3.0
2. CHADS Score >1 (CVA risk >4% per year): Warfarin or Aspirin
3. CHADS Score 0: Aspirin 81 to 325 mg daily
References
1. Gage (2004) Circulation 110:2287

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