II. Indications

  1. Localized Prostate Cancer (Stages A to C)

III. Technique

  1. Permanent radioactive seed implants into Prostate
    1. Iodine 125
    2. Palladium 103
  2. Seeds precisely geometric arranged by computer

IV. Efficacy

  1. Appears effective as conventional Prostate Radiotherapy

V. Advantages over External Beam Prostate Radiotherapy

  1. Higher radiation dose with less adverse effects
  2. Avert daily Radiation Therapy for 4 to 6 weeks

VI. Adverse Effects

  1. Acute irritative uropathy for first 3 months
    1. Urinary urgency
    2. Dysuria and Pelvic Pain
    3. Urinary frequency
  2. Urinary Incontinence (1%)
  3. Impotence (30 to 50%)
  4. Rectal irritation (3 to 10%)
    1. Diarrhea
    2. Stool Urgency
    3. Tenesmus
    4. Rectal Bleeding

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