II. Indications

III. Mechanism

  1. Alpha 2 Adrenergic Receptor Antagonist
  2. See Penile Anatomy and Erection physiology

IV. Efficacy

  1. Subjective improvement in 40% of men with Impotence
  2. Slightly better than Placebo

V. Dose

  1. Yohimbine 5.4 mg PO tid

VI. Adverse Effects

  1. Nausea
  2. Irritability
  3. Hypertension

VII. Cost

  1. Month supply: $25

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Ontology: yohimbine (C0724441)

Definition (MSH) A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of ERECTILE DYSFUNCTION.
Definition (CSP) plant alkaloid with alpha-2-adrenergic blocking activity; has been used as a mydriatic and in the treatment of impotence.
Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH D015016
SnomedCT 398674007, 73407000
LNC LP35686-2, MTHU018491
English Yohimbine, Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16alpha,17alpha)-, corynine, quebrachine, Yohimbe, Yohimbine [Chemical/Ingredient], yohimbe, yohimbine, YOHIMBINE, Yohimbine (product), Yohimbine (substance)
Swedish Yohimbin
Czech yohimbin
Finnish Johimbiini
Russian RAUVOL'STSIN, IOKHIMBIN, ИОХИМБИН, РАУВОЛЬСЦИН
Japanese ラウオルシン, ヨヒンビン
Croatian Not Translated[Yohimbine]
Polish Johimbina
Spanish yohimbina (producto), yohimbina (sustancia), yohimbina, Yohimbina
French Yohimbine
German Yohimbin
Italian Yohimbina
Portuguese Ioimbina