II. Indications

  1. Psychogenic Impotence
  2. Neurogenic Impotence
  3. Vasculogenic Impotence

III. Contraindications

IV. Preparation

  1. Transurethral preparation
    1. Inserted 3 cm into Urethra with plastic applicator
  2. Semi-solid pellet
    1. Diameter: 1.4 mm
    2. Length: 3-6 mm

V. Efficacy

  1. Successful intercourse in 65% of 1511 tested
  2. Placebo success rate: 19%
  3. Less effective than injectable alprostadil

VI. Adverse effects

  1. Hypotension (3%)
  2. Dizziness (2%)
  3. Mild Erectile discomfort (32%)
  4. Minor Urethral burning or bleeding
  5. Priapism is rare

VII. Dosing

  1. Dose 125-1000 ug ($114-$137 for 6 units)

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Cost: Medications

muse (on 1/9/2016 at Medicaid.Gov Survey of pharmacy drug pricing)
MUSE 1,000 MCG URETHRAL SUPP $62.96 each

Ontology: Prostin VR (C0592016)

Concepts Pharmacologic Substance (T121) , Eicosanoid (T111)
MSH D000527
English Prostin VR Pediatric, prostin vr, prostin vr pediatric, Astra Brand of Alprostadil, Janssen Brand of Alprostadil, Prostin VR, Minprog, Prostine VR, AstraZeneca Brand of Alprostadil, Paladin Brand of Alprostadil, Pharmacia Brand 1 of Alprostadil, Vivus Brand of Alprostadil, Abbott Brand of Alprostadil
French Prostine VR