II. Indication

  1. Confirmation of proteiunuria on Urine Protein dipstick
  2. Replaced with Urine Protein to Creatinine Ratio

III. Efficacy

  1. Highly sensitive for Urine Protein
  2. Detects light chain proteins

IV. Technique

  1. Urine mixed with 3% to 5% Sulfosalicylic acid (SSA)
  2. Urine turbidity measured with photometer
  3. Variation in results may be as much as 20%

V. Interpretation: Positive Test

VI. Interpretation: False positive causes

  1. Radiographic contrast agents (in last 3 days)
  2. Tolbutamide
  3. Penicillins
  4. Sulfisoxazole

VII. Interpretation: Negative Test

  1. False Proteinuria
  2. Renal Tubules not reabsorbing

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