II. Score

  1. Grade dominant Prostate tumor on scale 1 to 5
  2. Grade other histologic patterns on scale 1 to 5
  3. Sum 2 grades for total score of 2 to 10 for tumor

III. Interpretation of Prostate Cancer histology

  1. Grade 2 suggests highly differentiated tumor (best)
  2. Grade 10 suggests undifferentiated tumor (worst)

IV. Reference

  1. Wilson (1991) Harrison's Internal Medicine, p. 1630

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Ontology: Gleason Grading System (C0332326)

Definition (MSH) System of grading PROSTATE CANCER based on the degree of abnormality of the glandular archtecture of the tumor.
Definition (NCI) A grading system for prostatic carcinoma based on the microscopic glandular architectural patterns of the malignant epithelial cells. Nuclear atypia is not evaluated. It defines five patterns or grades which reflect decreasing differentiation.
Concepts Classification (T185)
MSH D060787
SnomedCT 393947006, 394930000, 392991003, 106241006
Spanish sistema de puntaje de Gleason para cáncer prostático, clasificación de Gleason del cáncer prostático, clasificación de Gleason del cáncer prostático (escala de estadificación), sistema de clasificación de Gleason mediante microscopia del carcinoma prostático (escala de estadificación), sistema de clasificación de Gleason mediante microscopia del carcinoma prostático, sistema de puntaje de Gleason mediante microscopia del carcinoma prostático (escala de estadificación), sistema de puntaje de Gleason mediante microscopia del carcinoma prostático, sistema de puntaje de Gleason para cáncer prostático (escala de estadificación), sistema de puntaje de Gleason para del cáncer prostático
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French Évaluation du grade de Gleason, Grading de Gleason, Détermination du grade de Gleason, Établissement du grade de Gleason
Czech Gleasonův systém
German Gleason-Klassifikation
Norwegian Gleason-gradering