II. Causes: Inflammatory or Papulosquamous

  1. Angiokeratoma
    1. Red-blue Papules along the margin of the glans penis
    2. Distinguish from Pearly Penile Papules
  2. Lichen Nitidus
    1. Tiny (1 mm) hypopigmented Papules
    2. Often found on non-genital skin
    3. Distinguish from Genital Herpes and pearly penile Papules
  3. Lichen Planus
    1. Pruritic, sore, flat-topped polygonal violaceous Papules
    2. Often found on non-genital skin
    3. Distiniguish from Secondary Syphilis
    4. Responds to Topical Corticosteroids
  4. Lichen Sclerosus of foreskin
    1. Cellophane-like hypopigmented, thinned foreskin
    2. May result in Phimosis, urinary outflow obstruction, painful Erections
    3. Pruritus and bleeding may also occur
    4. Distinguish from Scleroderma and Penile Cancer
    5. Responds to Topical Corticosteroids
  5. Psoriasis
    1. Red Plaques with overlying scale
    2. Isolated involvement of the genital skin without Plaques elsewhere would be rare
    3. Distinguish from Bowen Disease
    4. Responds to Topical Corticosteroids

III. Causes: Infectious

IV. Causes: Neoplastic

  1. Penile Cancer in Situ (Bowen Disease)
  2. Penile invasive squamous cell cancer

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